Double-Blind, Parallel-Group Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer’s Disease
NCT00478205, EU CTR 2006-004888-54
Jun 2007 - Jun 2009
The primary objective of this study was to compare the efficacy of donepezil sustained release (SR) 23 mg with donepezil immediate release (IR) 10 mg in the treatment of patients with moderate to severe Alzheimer's disease.
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Publication reference citation
Farlow MR, Salloway S, Tariot PN, Yardley J, Moline ML, Wang Q, et al. Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer’s disease: A 24-week, randomized, double-blind study. Clin Ther. 2010;32:1234-51.
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Redacted documents are available upon request for this study.